Pardridge, William M: search on Z-Library

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1

DRUG AND GENE TARGETING TO THE BRAIN WITH MOLECULAR TROJAN HORSES

Pardridge, William M.

Journal:

Nature Reviews Drug Discovery

Year:

2002

Language:

english

File:

PDF, 1.01 MB

english, 2002

2

Brain drug delivery and blood–brain barrier transport

Pardridge, William M.

Journal:

Year:

1996

Language:

english

File:

PDF, 1.95 MB

english, 1996

3

Transport of Albumin-bound Melatonin Through the Blood-Brain Barrier

William M. Pardridge, Lawrence J. Mietus

Journal:

Journal of Neurochemistry

Year:

1980

Language:

english

File:

PDF, 294 KB

english, 1980

4

Two-Day Starvation Does Not Alter the Kinetics of Blood-Brain Barrier Transport and Phosphorylation of Glucose in Rat Brain

Crane, Paul D., Pardridge, William M., Braun, Leon D., Oldendorf, William H.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

1985

Language:

english

File:

PDF, 384 KB

english, 1985

5

Delivery of peptides and proteins through the blood–brain barrier

Ulrich Bickel, Takayoshi Yoshikawa, William M. Pardridge

Journal:

Advanced Drug Delivery Reviews

Year:

2001

Language:

english

File:

PDF, 1.44 MB

english, 2001

6

Translational science: what is it and why is it so important?

William M Pardridge

Journal:

Drug Discovery Today

Year:

2003

Language:

english

File:

PDF, 72 KB

english, 2003

7

Log(BB), PS products and in silico models of drug brain penetration

William M. Pardridge

Journal:

Drug Discovery Today

Year:

2004

Language:

english

File:

PDF, 31 KB

english, 2004

8

Chimeric peptides as a vehicle for peptide pharmaceutical delivery through the blood-brain barrier

William M. Pardridge, Arno K. Kumagai, Jody B. Eisenberg

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 514 KB

english, 1987

9

Molecular Trojan horses for blood–brain barrier drug delivery

William M Pardridge

Journal:

Current Opinion in Pharmacology

Year:

2006

Language:

english

File:

PDF, 229 KB

english, 2006

10

Amplification of gene expression using both 5′- and 3′-untranslated regions of GLUT1 glucose transporter mRNA

Ruben J. Boado, William M. Pardridge

Journal:

Molecular Brain Research

Year:

1999

Language:

english

File:

PDF, 236 KB

english, 1999

11

Strategies for drug delivery through the blood-brain barrier

Pardridge, William M.

Journal:

Neurobiology of Aging

Year:

1989

Language:

english

File:

PDF, 235 KB

english, 1989

12

CSF, blood-brain barrier, and brain drug delivery

Pardridge, William M.

Journal:

Expert Opinion on Drug Delivery

Year:

2016

Language:

english

File:

PDF, 922 KB

english, 2016

13

Measurement of Amyloid Peptide Precursor of Alzheimer Disease in Human Blood by Double Antibody Immunoradiometric Assay

Pardridge, William M., Buciak, Jody L., Yang, Jing, Miller, Bruce L., Vinters, Harry V.

Journal:

Alzheimer Disease & Associated Disorders

Year:

1991

File:

PDF, 673 KB

1991

14

Safety and clinical efficacy of AGT-181, a brain penetrating human insulin receptor antibody-iduronidase fusion protein, in a 26-week study with pediatric patients with mucopolysaccharidosis type I

Giugliani, Roberto, Giugliani, Luciana, Corte, Amauri Dalla, Poswar, Fabiano, Donis, Karina, Schmidt, Mathias, Hunt, Douglas, Boado, Ruben J., Pardridge, William M.

Journal:

Molecular Genetics and Metabolism

Year:

2018

Language:

english

File:

PDF, 52 KB

english, 2018

15

Immunohistochemical study of cerebral amyloid angiopathy. III. Widespread alzheimer A4 peptide in cerebral microvessel walls colocalizes with gamma trace in patients with leukoencephalopathy

Dr Harry V. Vinters, Diana Lenard Secor, William M. Pardridge, Françoise Gray

Journal:

Annals of Neurology

Year:

1990

Language:

english

File:

PDF, 1007 KB

english, 1990

16

Glucose transport and phosphorylation: Which is rate limiting for brain glucose utilization?

William M. Pardridge

Journal:

Annals of Neurology

Year:

1994

Language:

english

File:

PDF, 200 KB

english, 1994

17

Reply

William M. Pardridge

Journal:

Annals of Neurology

Year:

1994

Language:

english

File:

PDF, 130 KB

english, 1994

18

Humanization of anti-human insulin receptor antibody for drug targeting across the human blood–brain barrier

Ruben J. Boado, Yufeng Zhang, Yun Zhang, William M. Pardridge

Journal:

Biotechnology and Bioengineering

Year:

2007

Language:

english

File:

PDF, 283 KB

english, 2007

19

Genetic engineering, expression, and activity of a fusion protein of a human neurotrophin and a molecular Trojan horse for delivery across the human blood–brain barrier

Ruben J. Boado, Yufeng Zhang, Yun Zhang, William M. Pardridge

Journal:

Biotechnology and Bioengineering

Year:

2007

Language:

english

File:

PDF, 307 KB

english, 2007

20

Genetic engineering of a lysosomal enzyme fusion protein for targeted delivery across the human blood-brain barrier

Ruben J. Boado, Yun Zhang, Yufeng Zhang, Chun-fang Xia, Yuntao Wang, William M. Pardridge

Journal:

Biotechnology and Bioengineering

Year:

2008

Language:

english

File:

PDF, 347 KB

english, 2008

21

GDNF fusion protein for targeted-drug delivery across the human blood–brain barrier

Ruben J. Boado, Yun Zhang, Yufeng Zhang, Yuntao Wang, William M. Pardridge

Journal:

Biotechnology and Bioengineering

Year:

2008

Language:

english

File:

PDF, 255 KB

english, 2008

22

Engineering and expression of a chimeric transferrin receptor monoclonal antibody for blood–brain barrier delivery in the mouse

Ruben J. Boado, Yun Zhang, Yuntao Wang, William M. Pardridge

Journal:

Biotechnology and Bioengineering

Year:

2009

Language:

english

File:

PDF, 286 KB

english, 2009

23

IgG-single chain Fv fusion protein therapeutic for alzheimer's disease: Expression in CHO cells and pharmacokinetics and brain delivery in the rhesus monkey

Ruben J. Boado, Jeff Zhiqiang Lu, Eric Ka-Wai Hui, William M. Pardridge

Journal:

Biotechnology and Bioengineering

Year:

2010

Language:

english

File:

PDF, 499 KB

english, 2010

24

CHO cell expression, long-term stability, and primate pharmacokinetics and brain uptake of an IgG–paroxonase-1 fusion protein

Ruben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu, William M. Pardridge

Journal:

Biotechnology and Bioengineering

Year:

2011

Language:

english

File:

PDF, 466 KB

english, 2011

25

Expression in CHO cells and pharmacokinetics and brain uptake in the Rhesus monkey of an IgG-iduronate-2-sulfatase fusion protein

Jeff Zhiqiang Lu, Ruben J. Boado, Eric K.-W. Hui, Qing-Hui Zhou, William M. Pardridge

Journal:

Biotechnology and Bioengineering

Year:

2011

Language:

english

File:

PDF, 1.15 MB

english, 2011

26

Glucose and amino acid metabolism in an established line of skeletal muscle cells

William M. Pardridge, Mayer B. Davidson, Delia Casanello-Ertl

Journal:

Journal of Cellular Physiology

Year:

1978

Language:

english

File:

PDF, 673 KB

english, 1978

27

Glucose and amino acid metabolism in neonatal rat skeletal muscle in tissue culture

William M. Pardridge, Luiza Duducgian-Vartavarian, Delia Casanello-Ertl, Michael R. Jones, Joel D. Kopple

Journal:

Journal of Cellular Physiology

Year:

1980

Language:

english

File:

PDF, 668 KB

english, 1980

28

Comparison of cDNA and genomic forms of tyrosine hydroxylase gene therapy of the brain with Trojan horse liposomes

Chun-Fang Xia, Chun Chu, Jianyi Li, Yuntao Wang, Yun Zhang, Ruben J. Boado, William M. Pardridge

Journal:

The Journal of Gene Medicine

Year:

2007

Language:

english

File:

PDF, 340 KB

english, 2007

29

Intravenous glial-derived neurotrophic factor gene therapy of experimental Parkinson's disease with Trojan horse liposomes and a tyrosine hydroxylase promoter

Chun-Fang Xia, Ruben J. Boado, Yun Zhang, Chun Chu, William M. Pardridge

Journal:

The Journal of Gene Medicine

Year:

2008

Language:

english

File:

PDF, 455 KB

english, 2008

30

Receptor-mediated delivery of an antisense gene to human brain cancer cells

Yun Zhang, Hwa Jeong Lee, Ruben J. Boado, William M. Pardridge

Journal:

The Journal of Gene Medicine

Year:

2002

Language:

english

File:

PDF, 383 KB

english, 2002

31

Marked enhancement in gene expression by targeting the human insulin receptor

Yun Zhang, Ruben J. Boado, Dr. William M. Pardridge

Journal:

The Journal of Gene Medicine

Year:

2003

Language:

english

File:

PDF, 118 KB

english, 2003

32

In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats

Yun Zhang, Ruben J. Boado, William M. Pardridge

Journal:

The Journal of Gene Medicine

Year:

2003

Language:

english

File:

PDF, 136 KB

english, 2003

33

Organ-specific expression of the lacZ gene controlled by the opsin promoter after intravenous gene administration in adult mice

Chunni Zhu, Yun Zhang, Yu-feng Zhang, Jian Yi Li, Ruben J. Boado, William M. Pardridge

Journal:

The Journal of Gene Medicine

Year:

2004

Language:

english

File:

PDF, 380 KB

english, 2004

34

Enhanced cellular uptake and in vivo biodistribution of a monoclonal antibody following cationization

William M. Pardridge, Young-Sook Kang, Jing Yang, Jody L. Buciak

Journal:

Journal of Pharmaceutical Sciences

Year:

1995

Language:

english

File:

PDF, 737 KB

english, 1995

35

Ultrastructural localization of blood-brain barrier-specific antibodies using immunogold-silver enhancement techniques

Catherine L. Farrell, William M. Pardridge

Journal:

Journal of Neuroscience Methods

Year:

1991

Language:

english

File:

PDF, 962 KB

english, 1991

36

AGT-181: Expression in CHO cells and pharmacokinetics, safety, and plasma iduronidase enzyme activity in Rhesus monkeys

Ruben J. Boado, Eric K.-W. Hui, Jeff Zhiqiang Lu, William M. Pardridge

Journal:

Journal of Biotechnology

Year:

2009

Language:

english

File:

PDF, 547 KB

english, 2009

37

Selective targeting of a TNFR decoy receptor pharmaceutical to the primate brain as a receptor-specific IgG fusion protein

Ruben J. Boado, Eric Ka-Wai Hui, Jeff Zhiqiang Lu, Qing-Hui Zhou, William M. Pardridge

Journal:

Journal of Biotechnology

Year:

2010

Language:

english

File:

PDF, 609 KB

english, 2010

38

Chloroquine inhibits HIV-1 replication in human peripheral blood lymphocytes

William M Pardridge, Jing Yang, Amadou Diagne

Journal:

Immunology Letters

Year:

1998

Language:

english

File:

PDF, 73 KB

english, 1998

39

Glucose deprivation and hypoxia increase the expression of the GLUT1 glucose transporter via a specific mRNA cis-acting regulatory element

Ruben J. Boado, William M. Pardridge

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 96 KB

english, 2002

40

Measurement of Blood-Brain Barrier GLUT1 Glucose Transporter and Actin mRNA by a Quantitative Polymerase Chain Reaction Assay

Ruben J. Boado, William M. Pardridge

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 726 KB

english, 1994

41

Cis-Element/Cytoplasmic Protein Interaction Within the 3′-Untranslated Region of the GLUT1 Glucose Transporter mRNA

Kenneth J. Dwyer, Ruben J. Boado, William M. Pardridge

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 1.35 MB

english, 1996

42

Evidence for Translational Control Elements Within the 5′-Untranslated Region of GLUT1 Glucose Transporter mRNA

Ruben J. Boado, Haruhisa Tsukamoto, William M. Pardridge

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 1.15 MB

english, 1996

43

Brain Microvascular and Astrocyte Localization of P-Glycoprotein

William M. Pardridge, Pamela L. Golden, Young-Sook Kang, Ulrich Bickel

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 1.15 MB

english, 1997

44

Site-Directed Deletion of a 10-Nucleotide Domain of the 3′-Untranslated Region of the GLUT1 Glucose Transporter mRNA Eliminates Cytosolic Protein Binding in Human Brain Tumors and Induction of Reporter Gene Expression

Haruhisa Tsukamoto, Ruben J. Boado, William M. Pardridge

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 869 KB

english, 1997

45

Examination of Blood-Brain Barrier Transferrin Receptor by Confocal Fluorescent Microscopy of Unfixed Isolated Rat Brain Capillaries

Jörg Huwyler, William M. Pardridge

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 551 KB

english, 1998

46

CNS Drug Design Based on Principles of Blood-Brain Barrier Transport

William M. Pardridge

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 1.78 MB

english, 1998

47

Up-Regulation of Blood-Brain Barrier Short-Form Leptin Receptor Gene Products in Rats Fed a High Fat Diet

Ruben J. Boado, Pamela L. Golden, Nancy Levin, William M. Pardridge

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 678 KB

english, 1998

48

Rapid transferrin efflux from brain to blood across the blood–brain barrier

Yun Zhang, William M. Pardridge

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 289 KB

english, 2001

49

Expression of the neonatal Fc receptor (FcRn) at the blood–brain barrier

Felix Schlachetzki, Chunni Zhu, William M. Pardridge

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 147 KB

english, 2002

50

Site-directed mutagenesis of rabbit LAT1 at amino acids 219 and 234

Ruben J. Boado, Jian Yi Li, William M. Pardridge

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 826 KB

english, 2003

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